What is Cerezyme
Cerezyme Injection 400 Units is a man-made form of an enzyme that occurs naturally in the body. It is used as an enzyme replacement in people with Type I Gaucher disease.
Gaucher disease is a genetic condition in which the body lacks the enzyme needed to break down certain fatty materials (lipids). Lipids can build up in the body, causing symptoms such as easy bruising or bleeding, weakness, anemia, bone or joint pain, enlarged liver or spleen, or weakened bones that are easily fractured.
Cerezyme Injection 400 Units may improve the condition of the liver, spleen, bones, and blood cells in people with Type I Gaucher disease. However, this medicine is not a cure for this condition.
Cerezyme Injection may also be used for purposes other than those listed in this medication guide.
Symptoms of allergic reactions including difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; hives; itching; flushing; and dizziness or fainting, have occurred with the use of Cerezyme Injection 400 Units. Approximately 15% of patients treated with Cerezyme Injection 400 Units develop antibodies to imiglucerase. Approximately 46% of patients with detectable antibodies have experienced an allergic reaction. Emergency medical attention may be required if an allergic reaction is experienced.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before using Cerezyme Injection 400 Units
You should not use Cerezyme Injection 400 Units if you are allergic to imiglucerase.
To make sure Cerezyme injection is safe for you, tell your doctor if you have:
a breathing problem such as pneumonia or pulmonary hypertension.
FDA pregnancy category C. It is not known whether Cerezyme Injection 400 Units will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
It is not known whether imiglucerase passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Cerezyme should not be given to a child younger than 2 without a doctor’s advice.
How should I use Cerezyme Injection
Cerezyme is injected into a vein through an IV. A healthcare provider will give you this injection.
Cerezyme Injection 400 Units is usually given every 2 weeks, but you may need the medicine more often when you first start using it. Follow your doctor’s dosing instructions very carefully.
You may be given other medicines to prevent certain side effects of Cerezyme Injection 400 Units. Take these medicines exactly as directed.
Tell your doctor if you have any changes in weight. Cerezyme Injection 400 Units doses are based on weight.
What happens if I miss a dose
Call your doctor for instructions if you miss a dose of Cerezyme Injection 400 Units OR Contact Ozisik Eczane
What happens if I overdose
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid while using Cerezyme Injection
Follow your doctor’s instructions about any restrictions on food, beverages, or activity.
Cerezyme Injection side effects
Get emergency medical help if you have any of these signs of an allergic reaction to Cerezyme Injection 400 Units: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during or shortly after the injection. Tell your caregiver right away if you feel dizzy, itchy, light-headed, sweaty, or have chest pain, cough, trouble breathing, or flushing (warmth, redness, or tingly feeling).
Call your doctor at once if you have:
- fever, chills, cough with yellow or green mucus;
- stabbing chest pain, wheezing, feeling short of breath; or
- worsening or no improvement in your Gaucher disease symptoms.
Common Cerezyme Injection 400 Units side effects may include:
- stomach pain, nausea, vomiting, diarrhea;
- fast heartbeats;
- headache, dizziness;
- back pain;
- fever, chills, tired feeling;
- mild rash; or
- itching, burning, swelling, or other discomfort around the IV needle.
What other drugs will affect Cerezyme Injection
Other drugs may interact with imiglucerase, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. Cerezyme drug interactions