What Is Harvoni

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Harvoni (ledipasvir and sofosbuvir) is a medicine that treats chronic hepatitis C virus (HCV), an infectious liver disease. Harvoni is one product that contains two drugs: ledipasvir and sofosbuvir. It belongs to a class of drugs called direct-acting antivirals (DAAs). Ledipasvir and sofosbuvir are both antiviral drugs that inhibit proteins that HCV needs in order to replicate and survive. Harvoni comes as a tablet and as pellets, both taken by mouth. It is available generically.

How To Use Harvoni 90mg/400mg

Harvoni is used to treat hepatitis C. Hepatitis C is a liver infection caused by the hepatitis C virus (HCV). HCV can lead to severe liver damage.

HCV affects everyone differently. For some individuals, the infection is mild and clears spontaneously. In others, it becomes a persistent infection that can progress to a life-threatening condition. The goal of treating HCV with medicines like Harvoni is to suppress the hepatitis C virus to the point at which it is not detectable in your blood.

How to Take Harvoni

Take Harvoni at the same time every day with or without food. Take it when you are most able to remember it so that you don’t accidentally miss doses. It’s important to take Harvoni according to the regimen prescribed by your healthcare provider. Buy Harvoni 90mg/400mg

In addition to a tablet, Harvoni is available as oral pellets. You can sprinkle the pellets on nonacidic foods that are at or below room temperature (between 68 and 77 degrees Fahrenheit), such as pudding, mashed potatoes (cooled down), or ice cream. Take Harvoni pellets within 30 minutes of mixing them with food. Swallow the food without chewing to avoid a bitter aftertaste from the pellets.

Side Effects of Harvoni

Common Side Effects

Common side effects when taking Harvoni include:

Headache
Fatigue, or feeling generally tired and sleepy
Weakness

Severe Side Effects

Potential side effects of Harvoni that were rarer in clinical trials but potentially more severe include:

Hepatitis B reactivation
Psychiatric disorders such as depression, especially in individuals with a history of psychiatric illness
Abnormal lab testing results such as bilirubin, lipase, or creatine kinase elevations
Serious bradycardia (slow heart rate) in people who start Harvoni while they are also taking a drug called amiodarone

Call your healthcare provider right away if you have serious side effects

Long-Term Side Effects

Harvoni must be taken for a specified amount of time to treat hepatitis C. This time frame is different depending on the individual but generally ranges from eight to 24 weeks. The side effects mentioned above apply to this time range. There are no other side effects particularly associated with long-term use of the medicine.

Precautions

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Using this medicine together with ribavirin while you are pregnant can harm your unborn baby. These medicines may also cause birth defects if the father is using it when his sexual partner becomes pregnant. If a pregnancy occurs while you are using these medicines and for 6 months after your treatment ends, tell your doctor right away.

Using this medicine with amiodarone may cause bradycardia. Check with your doctor right away if you have chest pain or discomfort, lightheadedness, dizziness, or fainting, shortness of breath, slow or uneven heartbeat, or unusual tiredness.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John’s wort) or vitamin supplements.

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