What Is Harvoni
Harvoni (ledipasvir and sofosbuvir) is a medicine that treats chronic hepatitis C virus (HCV), an infectious liver disease. Harvoni is one product that contains two drugs: ledipasvir and sofosbuvir. It belongs to a class of drugs called direct-acting antivirals (DAAs). Ledipasvir and sofosbuvir are both antiviral drugs that inhibit proteins that HCV needs in order to replicate and survive. Harvoni comes as a tablet and as pellets, both taken by mouth. It is available generically.
How To Use Harvoni 90mg/400mg
How to Take Harvoni
Side Effects of Harvoni
Common Side Effects
- Fatigue, or feeling generally tired and sleepy
Severe Side Effects
- Hepatitis B reactivation
- Psychiatric disorders such as depression, especially in individuals with a history of psychiatric illness
- Abnormal lab testing results such as bilirubin, lipase, or creatine kinase elevations
- Serious bradycardia (slow heart rate) in people who start Harvoni while they are also taking a drug called amiodarone
Long-Term Side Effects
Harvoni must be taken for a specified amount of time to treat hepatitis C. This time frame is different depending on the individual but generally ranges from eight to 24 weeks. The side effects mentioned above apply to this time range. There are no other side effects particularly associated with long-term use of the medicine.